Microtome Types and Applications
Different types of microtome are used to section different types of tissue, depending on the sample’s size, embedding medium, and preparation method.
May 25, 2023
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Different types of microtome are used to section different types of tissue, depending on the sample’s size, embedding medium, and preparation method.
Dr. Mike Taormina uses SmartSPIM light sheet microscopy to rapidly image whole mouse brains, streamlining workflows at the Allen Institute.
Light sheet fluorescence and laser scanning confocal microscopy are both used to acquire 3D image datasets with optical sectioning, however they differ significantly in imaging speed and resulting data quality.
The Allen Brain Atlas is an incredibly powerful tool for neuroscience research, enabling researchers to discuss their findings in a common coordinate system.
Dr. Michelle Bedenbaugh uses SmartSPIM microscopy and SmartAnalytics to visualize and quantify MC3R circuitry in whole mouse brains.
Ph.D. candidate Kaitlyn Dorst uses LifeCanvas CRO services to investigate the underpinnings of fear memories in mice.