Dr. Sam Centanni uses the LifeCanvas pipeline to investigate the neurobiological overlap between stress and predisposition to alcohol abuse, as well as long-term effects of alcohol on the brain.
Dr. Mike Taormina uses SmartSPIM light sheet microscopy to rapidly image whole mouse brains, streamlining workflows at the Allen Institute.
Light sheet fluorescence and laser scanning confocal microscopy are both used to acquire 3D image datasets with optical sectioning, however they differ significantly in imaging speed and resulting data quality.
The Allen Brain Atlas is an incredibly powerful tool for neuroscience research, enabling researchers to discuss their findings in a common coordinate system.
Dr. Michelle Bedenbaugh uses SmartSPIM microscopy and SmartAnalytics to visualize and quantify MC3R circuitry in whole mouse brains.
Dr. Kim’s lab at Penn State uses the SmartSPIM light sheet microscope to map and create 3D atlases of the developing mouse brain.