Light sheet fluorescence and laser scanning confocal microscopy are both used to acquire 3D image datasets with optical sectioning, however they differ significantly in imaging speed and resulting data quality.
The Allen Brain Atlas is an incredibly powerful tool for neuroscience research, enabling researchers to discuss their findings in a common coordinate system.
Dr. Michelle Bedenbaugh uses SmartSPIM microscopy and SmartAnalytics to visualize and quantify MC3R circuitry in whole mouse brains.
Dr. Kim’s lab at Penn State uses the SmartSPIM light sheet microscope to map and create 3D atlases of the developing mouse brain.
Dr. Ye’s lab at the Scripps Research Institute uses SmartSPIM to illuminate interactions between the central and peripheral nervous systems.
LifeCanvas’ SmartSPIM light sheet microscope rapidly acquires high-resolution images from whole tissue samples.