End-to-End Solutions
for 3D Spatial Biology

LifeCanvas is revolutionizing 3D spatial biology with powerful end-to-end solutions for tissue preservation, sectioning, clearing, immunolabeling, and imaging, advancing biomedical research, drug discovery, personalized medicine, and disease diagnostics.

Integrated solutions, sample-to-data processing, & expert support for an unparalleled range of applications.

From neuroscience to oncology, whole organs to organoids, LifeCanvas offers a unique end-to-end pipeline tailor-made for your research application. Our automated tools and proprietary technologies will streamline your workflow and improve your data outputs with unprecedented speed, accuracy, depth, and cost-effectiveness. We partner with you to obtain unbiased data that will drive your studies forward and enable breakthrough discoveries.

Sample Preparation

Optimize samples for imaging with advanced techniques for tissue preservation, tissue clearing, and immunolabeling.

Light Sheet Imaging

Easily capture 3D image data from a wide range of tissue types and sizes with unmatched acquisition speed and resolution.

3D Data Analysis

Leverage AI-powered cell detection algorithms to generate robust analysis outputs from 3D image data.

Recently published studies

Classification of psychedelic drugs based on brain-wide imaging of cellular c-Fos expression

Farid Aboharb, View ORCID ProfilePasha A. Davoudian, Ling-Xiao Shao, View ORCID ProfileClara Liao, Gillian N. Rzepka, Cassandra Wojtasiewicz, Mark Dibbs, Jocelyne Rondeau, Alexander M. Sherwood, View ORCID ProfileAlfred P. Kaye, View ORCID ProfileAlex C. Kwan.

Journal:
Nature Communications
Publication Date:
Research Area:
Neural Circuits
Tissue Species:
Mouse
Tissue Type:
Brain
Products Cited:
CRO Services
A deep learning pipeline for three-dimensional brain-wide mapping of local neuronal ensembles in teravoxel light-sheet microscopy

Ahmadreza Attarpour, Jonas Osmann, Anthony Rinaldi, Tianbo Qi, Neeraj Lal, Shruti Patel, Matthew Rozak, Fengqing Yu, Newton Cho, Jordan Squair, JoAnne McLaurin, Misha Raffiee, Karl Deisseroth, Gregoire Courtine, Li Ye, Bojana Stefanovic & Maged Goubran

Journal:
Nature Methods
Publication Date:
Tissue Species:
Mouse
Tissue Type:
Brain
Products Cited:
SHIELD, EasyIndex, SmartBatch+, CRO Services
Uniform volumetric single-cell processing for organ-scale molecular phenotyping

Dae Hee Yun, Young-Gyun Park, Jae Hun Cho, Lee Kamentsky, Nicholas B. Evans, Nicholas DiNapoli, Katherine Xie, Seo Woo Choi, Alexandre Albanese, Yuxuan Tian, Chang Ho Sohn, Qiangge Zhang, Minyoung E. Kim, Justin Swaney, Webster Guan, Juhyuk Park, Gabi Drummond, Heejin Choi, Luzdary Ruelas, Guoping Feng & Kwanghun Chung

Journal:
Nature Biotechnology
Publication Date:
Products Cited:
SHIELD

LifeCanvas Portraits: Conversations with researchers

LifeCanvas Portraits: Dr. Paula Montero Llopis

Dr. Montero Llopis shares her insights on the MicRoN Core’s vision, its adoption of LifeCanvas technologies, and how our values align to support scientific advancement.

LifeCanvas Portraits: Tanya Daigle

Dr. Tanya Daigle used LifeCanvas' Services to acquire 3D images of spinal motor neurons illuminated by enhancer AAV.

LifeCanvas Portraits: Dr. Sam Centanni

Dr. Sam Centanni uses the LifeCanvas pipeline to investigate the neurobiological overlap between stress and predisposition to alcohol abuse, as well as long-term effects of alcohol on the brain.

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