Our novel SHIELD tissue preservation technique forms intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids. SHIELD avoids the variability of hydrogel embedding and the information loss from PFA preservation, protecting specimens for multiple rounds of processing.
Our new Clear+ tissue clearing technique is the only method that delipidates samples with no change in morphology and with minimal impact on structural integrity. Fully delipidate whole mouse brains or comparably sized samples in just one day with SmartBatch+, or in one week with our passive clearing kit.
Our turn-key SmartBatch+ system combines electrophoretic tissue clearing and immunolabeling into one high-throughput device. Leverage the Clear+ tissue clearing method, along with eFLASH and patented stochastic electrotransport technologies, to rapidly clear and label whole organs. Key highlights and features include:
Megatome is a vibrating microtome designed to section a broad range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables high-throughput tissue sectioning with uniform surface profile, as well as minimal tissue damage and information loss. Additional features include mounting accessories, remote desktop control, and close-up cameras to facilitate the sectioning process.