End-to-end solutions for
3D spatial biology

LifeCanvas’ pipeline empowers scientists with spatially-resolved insights from intact tissues. Accelerate your studies with high-resolution, high-throughput readouts, all while maintaining biologically accurate morphology.

Streamlining bioimaging,
from sample to data.

From neuroscience to oncology, whole organs to organoids, LifeCanvas offers a unique end-to-end pipeline tailor-made for your research application. Our tools will simplify your workflow and improve your data outputs with unprecedented speed, accuracy, depth, and cost-effectiveness. We partner with you to obtain unbiased data that will drive your studies forward and enable breakthrough discoveries.

Sample Preparation

Optimize samples for imaging with advanced techniques for tissue preservation, clearing, and labeling.

Light Sheet Imaging

Easily capture 3D image data from a wide range of tissue types and sizes with unmatched acquisition speed and resolution.

3D Data Analysis

Leverage AI-powered cell detection algorithms to generate robust analysis outputs from 3D image data.

Introducing DALISPIM

Open-top light sheet microscope for easy, scalable imaging workflows

Our newest system packs the resolution and speed of our other microscopes into an open-top, inverted configuration. DALISPIM is readily automatable and perfect for seamless high-throughput imaging, from whole tissues in multiwell plates to slide-mounted sections and beyond.

Recently published studies

Topographic structure and function of locus coeruleus noradrenaline neurons

Zhixiao Su, Polina Kosillo, Kanghoon Jung, Shuonan Chen, Mathew T. Summers, Alex Piet, Han Hou, Kenta M. Hagihara, Drew Friedmann, Olivia Ho-Shing, Matthew I. Becker, Thomas Chartrand, Xinxin Yin, Peter Grotz, Ella Hilton-VanOsdall, Margaret Lee, Rajvi Javeri, Samantha L. Tuggle, Naveen Ouellette, Holly Myers, Judith Baka, Camilo Laiton, Kaelin Wulf, John Rohde, Alessio P. Buccino, Cameron Arshadi, Di Wang, Sharmishtaa Seshamani, Sonya Vasquez, Carolyn M. Eng, Douglas R. Ollerenshaw, Nick Dee, Tamara Casper, Windy Ho, Matthew Jungert, Atlas Jordan, Elliot Phillips, Anish Bhaswanth Chakka, Kamiliam Nasirova, Krista Blake, Audrey McCutcheon, Megan Koch, Maria Camila Vergara, Kimberly A. Smith, Tim Jarsky, Nicholas Lusk, Mara C. P. Rue, Xiaoyin Chen, Joshua H. Siegle, Adam K. Glaser, Brian R. Lee, Karel Svoboda, Yoh Isogai, Jayaram V. Chandrashekar & Jeremiah Y. Cohen

Journal:
Nature
Publication Date:
Research Area:
Neural Circuits
Tissue Species:
Mouse
Tissue Type:
Brain
Products Cited:
EasyIndex, SmartBatch+, SmartSPIM
A queen odour mediates reproductive suppression in a eusocial mammal

Mohammed A. Khallaf, Daniel W. Hart, Wenhan Luo, Firdevs Murad, Felipe Cybis Pereira, Daniel Mendez-Aranda, Nicole Hagenah, Alice Rossi, Valérie Bégay, Jan Okrouhlík, Dietmar Krautwurst, Mungo Kisinza Ngalameno, Andre Ganswindt, Alison J. Barker, Radim Šumbera, Markus Knaden, Sophie Pezet, Andrew Woehler, Bill S. Hansson, Nigel C. Bennett & Gary R. Lewin

Journal:
Nature
Publication Date:
Research Area:
Neural Activity
Tissue Type:
Brain
Products Cited:
SHIELD, EasyIndex, SmartClear, SmartLabel, SmartBatch+, Passive Clearing Kit, SmartSPIM, CRO Services
The prelimbic cortex arbitrates memory-guided conflict resolution

Albit Caban-Murillo, Michelle Surets, Celine Chien, Marine Kaufmann, Sarah Park, Steve Ramirez

Journal:
Current Biology
Publication Date:
Research Area:
Neural Activity
Tissue Species:
Mouse
Tissue Type:
Brain
Products Cited:
CRO Services

LifeCanvas Portraits: Conversations with our scientific community

The neuroscience of stress & alcohol use with Tatiyana Adkins

Tatiyana Adkins is the lead author on a recent JNeurosci paper uncovering the neural circuitry behind alcohol drinking and aversive behavior. We talked to Tatiyana about her findings and the technologies that made them possible.

Headshot of Dr. Paula Montero Llopis: A person with curly hair smiles softly, wearing a black floral-patterned top. The blurred background suggests an indoor setting.

LifeCanvas Portraits: Dr. Paula Montero Llopis

Dr. Montero Llopis shares her insights on the MicRoN Core’s vision, its adoption of LifeCanvas technologies, and how our values align to support scientific advancement.

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