Illuminating life like never before

Pioneering solutions for spatial biology:

Turn-key solutions and expert support with every step

Figure 1. SHIELD cross-links biological samples.
Tissue Preservation
Delipidation
Delipidation
Immunolabeling
Immunolabeling
Clearing
Optical Clearing
Imaging
Light Sheet Imaging
analysis
3D Image Analysis

Optimized tissue processing products

For superior tissue preservation, start with SHIELD. To improve your optical tissue clearing, use our easy and effective Clear+ active and passive tissue clearing methods with EasyIndex. Need immunolabeling solutions? Our active immunolabeling results in uniform, high quality tissue staining that rivals traditional immunohistochemistry (IHC).

Leverage the full power of our pipeline by using these reagents with our user-friendly devices. Process intact samples with SmartBatch+, the only system on the market to perform active batch tissue clearing and immunolabeling. Then image your samples with our SmartSPIM light sheet microscope. Lastly, analyze your results with SmartAnalytics software to produce stunning publication-quality data.

In-house whole organ mapping services

Send us your PFA-fixed samples for in-house processing and experience the potential of owning our complete workflow. Our CRO services give you access to our extensive expertise and innovative tools in tissue processing, imaging, and analysis. Contact us to learn how you can radically improve your science and expedite discoveries.

We offer solutions for research projects from neuroscience — including cFOS neural activity mapping and neurodegenerative disease phenotyping — to other mammalian systems including spinal cord, kidney, lungs, and liver. Our versatile methods can be applied to explore endogenous fluorescence and a variety of stains and biomarkers in unique tissue types such as tumors and organoids.

Start accelerating your research today:

Register for June 15th Webinar with Taconic Biosciences

Dr. Adam Hall will be discussing the application of our technologies in molecular phenotyping of intact brain samples from Taconic Biosciences' robust Alzheimer's mouse models. Learn how to obtain precise, illuminating spatial data for accurately assessing disease progression and the impact of drug interventions.

c-FOS Brain Mapping:
Challenges & Solutions

Mapping expression of the immediate early gene c-FOS can help scientists track responses to a variety of stimuli. Principal Engineer Dr. Brian Nguyen discusses key considerations for studying c-FOS in neuroscience projects, including the power of whole brain mapping with 3D histology, microscopy, and analysis tools.

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