SmartClear II Pro

SmartClear II Pro

The Multi-Purpose Tissue Clearing System You’ve Been Waiting For

SmartClear II Pro is ideal for:

  • CLARITY (Chung, Nature, 2013)
  • SWITCH (Murray, Cell, 2015)
  • MAP (Ku, Nature Biotechnology, 2016)

Various Sample Holders

11mm (W) x 18mm (D) x 40mm (H) x 5
Clears 5 whole mouse brains

(3mm apart)
Clears up to 10 1~2mm thick slices

19mm (W) x 28mm (D) x 40mm (H) x 2
Clears 2 whole rat brains

4mm (D) x 18 holes
Clears up to 18 circular disk-shape tissues

15mm (bottom diameter) x 19mm (top diameter) x 40mm (H) x 2
Clears 2 whole rat brains.

Enjoy batch tissue-clearing while keeping costs low and samples protected

Multipurpose Function

Batch processing and customization: 5 whole mouse brains or 2 rat brains can be cleared simultaneously. Larger clearing chamber enables clearing of various sample types and sizes that can be customized according to your needs.

Cost-effective Clearing of Bulk Quantity

Cost-effective and Eco-friendly: New-generation buffer set lasts around 10 days without loss of its clearing ability. Lower running costs for samples as the same volume of buffer is used regardless of size and number of samples.

Fast, Easy, and Reliable

Fast & Easy: Order of magnitude faster than passive clearing. Our ready-to-use technologies bring plug-and-play options to clearing.

Reliable: Prevents tissue damage with Stochastic Electrotransport technology (Kim, PNAS, 2015). Our nanoporous membranes (patent-pending) eliminate tissue contamination, tissue browning, black precipitates and tissue deformation while providing uniform clearing.

Perfect Clearing with Maximal FP Signal Preservation

FP Signals: Maximum preservation of Fluorescent Protein (FP) signals with optimized buffers that maintain pH.

Optical Clarity: Minimum light scatter. Removes lipid best for best antibody diffusion. Optimal imaging and staining quality that is compatible with SmartLabel, our rapid staining system for intact samples.

Clearing Buffer

  • Optimized for tissue clearing
  • Long life time (up to 10 days)
  • Eco-Friendly

Optical Clearing Solution (RI=1.46)

  • Formulated for best performance with CLARITY, SWITCH, and MAP
  • Cost-effective and convenient