SmartLabel labels large intact samples an order of magnitude faster than passive techniques (≤ 24 hours vs. weeks to months). Our technology achieves unparalleled uniformity of signal intensity from surface to core, and our patent-pending nanoporous membranes eliminate tissue contamination and probe loss.
Simply load the buffers, your sample, and probes. Our system can simultaneously perform 2 distinct experiments thanks to its dual chamber design.
SmartLabel uses as little as 3 µg of antibody to label tissues the size of a whole mouse brain and prevents antibody depletion caused by excessive binding to superficial tissue sites.
SmartLabel works with many tissue preservation techniques which avoid the loss of endogenous fluorescence and tissue shrinkage present in organic solvent-based clearing methods. SmartLabel is compatible with:
Rapid tissue clearing can be achieved with SmartBatch+ or SmartClear II Pro.
Augusto Ortega Granillo, Fengyan Deng, Hannah Wilson, Yongfu Wang, Alejandro Sánchez Alvarado
Trishna Shah, Sue E. Leurgans, Rashi I. Mehta, Jingyun Yang, Chad A. Galloway, Karen L. de Mesy Bentley, Julie A. Schneider, Rupal I. Mehta
Jacob Nelson, Lorenzo Ochoa, Paula Villareal, Tiffany Dunn, Ping Wu, Gracie Vargas, Alexander N. Freiberg