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Check out our new batch clearing and labeling device SmartBatch+!
Already own a SmartLabel? You’re eligible for our trade-in program: 40% off each SmartBatch+ for each SmartLabel you trade in.
Labels large, intact samples such as rodent organs an order of magnitude faster than with passive labeling (≤ 24 hours vs. weeks to months).
Turnkey operation: simply load the buffers, your sample, and probes. Performs 2 distinct labeling experiments simultaneously thanks to its dual chamber design.
Uses a small amount of antibody (as little as ~3 µg) to label tissues the size of a whole mouse brain.
Prevents tissue damage with stochastic electrotransport technology. Our nanoporous membranes (patent pending) eliminate tissue contamination and probe loss.
Achieves unparalleled uniformity of signal intensity from surface to core using LifeCanvas’s advanced eFLASH protocol.
Combines rapid, stochastic electrotransport-mediated infiltration of probes into tissue with the SWITCH technique of controlling probe binding kinetics.
Prevents antibody depletion caused by excessive binding to superficial tissue sites and ensures the sample’s center is well-labeled.
Volume rendering of anti-GFAP staining in a 2-mm thick section of mouse brain, with signal in CA1 hippocampus most prominent. Labeling achieved in 2 days using antibody electrophoresis performed by SmartLabel. Cleared with SmartClear II Pro (<1 day), refractive index-matched with EasyIndex, and light-sheet imaged with SmartSPIM (<4 minutes acquisition time with 2-µm z-step and 1.8 µm/pixel XY; 2×2 tile using a 3.6x, 0.2 NA objective). See more videos in the video gallery!
SmartLabel, the world’s first active labeling device, combines SWITCH and stochastic electrotransport technologies to quickly and uniformly label whole tissue samples in a fraction of the time needed for passive labeling. Stain an entire mouse brain or rat hemisphere in 24 hours or less and avoid the time-intensive, destructive sectioning and tedious image reconstruction of traditional histology.
