Complete: Full staining of organ-scale samples (e.g., mouse brain)
Uniform: Unparalleled signal uniformity throughout the sample
SmartLabel
The Ultimate Active Immunostaining Device
The Ultimate Active Immunostaining Device
Email us at labeling@lifecanvastech.com for more information.
Why Early Adopter?
- Competitive edge in whole-organ labeling and specialized technical support from our scientists
- Customized protocol development for your specific sample types and labels of interest
Rapid Immunostaining
with Unparalleled Uniformity
Fast, Easy, and Reliable
Fast, Easy, and Reliable
Fast: Order of magnitude faster than passive labeling (1-3 days compared to weeks or months)
Easy: Plug-and-play
Reliable: Prevents tissue damage with Stochastic Electrotransport technology (Kim, PNAS, 2015). Our nanoporous membranes (patent-pending) eliminate tissue contamination and probe loss.
Complete and Uniform Labeling
Complete and Uniform Labeling
Cost Savings by Avoiding Target Saturation
Cost Savings by Avoiding Target Saturation
Antibody savings: Complete and cost-effective labeling with a small amount of antibody by preventing antibody depletion
SmartLabel is compatible with many clearing techniques including:
- SWITCH (Murray, Cell, 2015)
- MAP (Ku, Nature Biotechnology, 2016)
- SHIELD (Park, Nature Biotechnology, 2018)
Anti-GFAP Staining in CA1 Hippocampus of 2-mm Thick Section of Mouse Brain
Volume rendering of anti-GFAP staining in a 2-mm thick section of mouse brain, with signal in CA1 hippocampus most prominent. Labeling achieved in 2 days using antibody electrophoresis performed by SmartLabel. Cleared with SmartClear II Pro (<1 day), refractive index-matched with EasyIndex, and light-sheet imaged with SmartSPIM (<4 minutes acquisition time with 2-µm z-step and 1.8 µm/pixel XY; 2×2 tile using a 3.6x, 0.2 NA objective).
SmartLabel: Rapid Immunostaining with Unparalleled Uniformity
SmartLabel, the world’s first active labeling device, combines SWITCH and stochastic electrotransport technologies to quickly and uniformly label whole tissue samples in a fraction of the time needed for passive labeling. Stain an entire mouse brain or rat hemisphere in just 2 days and avoid the time-intensive, destructive sectioning and tedious image reconstruction of traditional histology.
© Copyright LifeCanvas Technologies 2019. All Rights Reserved