LifeCanvas Wiki

Mouse Brain: Goat CD13 / Aminopeptidase N

Antibody link: R&D Systems AF2335

Goat CD13 / Aminopeptidase N staining in a whole mouse brain (40 µm max intensity projection).

Zoom in of hippocampus (left) and cerebellum (right) below.

Protocol

1. Standard SHIELD protocol.

2. Passive delipidation with Clear+ Delipidation Buffer.

3. 2 days blocking with Blocking Buffer at 37°C.

4. Radiant Labeling in SmartBatch+ using 5 µg Goat Anti-CD13 antibody in the Single Sample Staining Cup.

5. Secondary Labeling with 10 µg Donkey anti-Goat SeTau-647 in SmartBatch+.

6. EasyIndex index matching and mounting.

7. Imaged on SmartSPIM with 3.6X objective.