Alzheimer’s biomarkers in 3D: A new perspective on an aging disease

Immunolabeled GFAP (cyan) and Beta-amyloid plaques (magenta) in a 5xFAD mouse brain model of Alzheimer’s disease. Scale bar = 100 µm, 15X objective. Sample courtesy of Epp Lab, University of Calgary.

In 1906 at the University of Munich the neuropathologist Dr. Alois Alzheimer (Figure 1) was studying the brain of a recently deceased patient, Auguste Deter. Previously Alzheimer had assisted Frau Deter in the city asylum in Frankfurt and observed that she suffered from memory loss, delusions and dementia. Working in Dr. Emil Kraepelin’s lab in Munich… Continue reading Alzheimer’s biomarkers in 3D: A new perspective on an aging disease