Trace Local and Long-Range projections

Circuit Mapping Use Case: Trace Local and Long-Range Projections Map connected brain regions: Identify neuronal projections from a brain region and neuronal inputs to a brain region from every atlas defined region using anterograde and retrograde virus tracing without having to section the brain. Reconstruct entire neurons: Make accurate reconstructions of elaborate axonal and dendritic […]

Phenotype Peripheral Nerve Innervation Patterns

Circuit Mapping Use Case: Phenotype Peripheral Nerve Innervation Patterns Connect brain and periphery: Discover how different molecularly-defined neurons come together to send signals from the brain to organs and from the organs back to brain by tracing the neuronal connections between them using viral, transgenic, or immunolabeling strategies. Track disease progression: Follow the worsening or […]

Discover anterograde and retrograde connections

Circuit Mapping Use Case: Discover anterograde and retrograde connections Delineate connections: Label mono-synaptically connected neurons using anterograde and retrograde viruses and comprehensively map them in brain atlas space at single cell resolution.  Localize projections: Identify dense projections that map to local and distant brain regions, revealing potential new circuits for further anatomical and functional investigation. […]