{"id":123,"date":"2021-11-15T14:37:37","date_gmt":"2021-11-15T14:37:37","guid":{"rendered":"https:\/\/lifecanvastech.com\/?page_id=123"},"modified":"2024-02-28T15:28:09","modified_gmt":"2024-02-28T15:28:09","slug":"shield","status":"publish","type":"page","link":"https:\/\/lifecanvastech.com\/products\/shield\/","title":{"rendered":"SHIELD"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"123\" class=\"elementor elementor-123\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5686097 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5686097\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-00ff88c\" data-id=\"00ff88c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-71aee46 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"71aee46\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8b0b5ec\" data-id=\"8b0b5ec\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-be1e273 elementor-widget elementor-widget-image\" data-id=\"be1e273\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 25-04-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1255\" height=\"215\" src=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png\" class=\"attachment-full size-full wp-image-2509\" alt=\"Tissue Preservation - Highlighted pipeline icon\" srcset=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png 1255w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons-300x51.png 300w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons-1024x175.png 1024w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons-768x132.png 768w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons-240x41.png 240w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons-600x103.png 600w\" sizes=\"(max-width: 1255px) 100vw, 1255px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cd22ee6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cd22ee6\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-fdfff86\" data-id=\"fdfff86\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8ce7de7 elementor-widget elementor-widget-heading\" data-id=\"8ce7de7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 25-04-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Exceptional tissue preservation<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-504c1f9 elementor-widget elementor-widget-text-editor\" data-id=\"504c1f9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 25-04-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Published by <a href=\"https:\/\/www.nature.com\/articles\/nbt.4281\" target=\"_blank\" rel=\"noopener\">Park et al. in <i>Nature Biotechnology<\/i> 2018<\/a>, our SHIELD reagent (AKA GE38) safeguards endogenous fluorescence, protein antigenicity, nucleic acids, and overall tissue architecture against physical and chemical stressors. The SHIELD tissue preservation method also protects tissue during fluorescent protein imaging and antibody labeling across multiple rounds.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b15b65 elementor-widget elementor-widget-text-editor\" data-id=\"8b15b65\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Compatible with:<\/p><ul><li>All PFA-fixed tissues and multiplexing<\/li><li><a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(15)01505-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415015056%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener\">SWITCH<\/a>,<a href=\"https:\/\/www.nature.com\/articles\/nbt.3641\" target=\"_blank\" rel=\"noopener\"> MAP<\/a>, <a href=\"https:\/\/lifecanvastech.com\/products\/smartbatch\/\">SmartBatch+<\/a>, and <a href=\"https:\/\/lifecanvastech.com\/products\/smartlabel\/\">SmartLabel<\/a><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5704e9d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5704e9d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1ca50f5\" data-id=\"1ca50f5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-685fa3f elementor-align-center elementor-widget elementor-widget-button\" data-id=\"685fa3f\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/lifecanvastech.com\/technology\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-left\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-question-circle\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">How does it work?<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-bb91b73 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"bb91b73\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-aa12395\" data-id=\"aa12395\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-f5b9715\" data-id=\"f5b9715\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c5edd19 elementor-widget elementor-widget-image\" data-id=\"c5edd19\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"633\" height=\"333\" src=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/GFP_RFP_Med.png\" class=\"attachment-full size-full wp-image-1512\" alt=\"GFP+ motor cortical neurons in whole mouse brain (left) and tdTomato+ in a mouse spinal cord cell-type (right)\" srcset=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/GFP_RFP_Med.png 633w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/GFP_RFP_Med-300x158.png 300w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/GFP_RFP_Med-600x316.png 600w\" sizes=\"(max-width: 633px) 100vw, 633px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Left: GFP+ motor cortical neurons, sample courtesy of Dr. Byungkook Lim, UCSD. Right: RFP+ spinal cord cells, sample courtesy of Dr. Helen Lai, UT Southwestern. Both imaged with SmartSPIM.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-49c96c3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"49c96c3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-74ee1e9\" data-id=\"74ee1e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-abfe84e elementor-widget elementor-widget-video\" data-id=\"abfe84e\" data-element_type=\"widget\" data-settings=\"{&quot;video_type&quot;:&quot;vimeo&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 25-04-2024 *\/\n.elementor-widget-video .elementor-widget-container{overflow:hidden;transform:translateZ(0)}.elementor-widget-video .elementor-wrapper{aspect-ratio:var(--video-aspect-ratio)}.elementor-widget-video .elementor-wrapper iframe,.elementor-widget-video .elementor-wrapper video{height:100%;width:100%;display:flex;border:none;background-color:#000}@supports not (aspect-ratio:1\/1){.elementor-widget-video .elementor-wrapper{position:relative;overflow:hidden;height:0;padding-bottom:calc(100% \/ var(--video-aspect-ratio))}.elementor-widget-video .elementor-wrapper iframe,.elementor-widget-video .elementor-wrapper video{position:absolute;top:0;right:0;bottom:0;left:0}}.elementor-widget-video .elementor-open-inline .elementor-custom-embed-image-overlay{position:absolute;top:0;right:0;bottom:0;left:0;background-size:cover;background-position:50%}.elementor-widget-video .elementor-custom-embed-image-overlay{cursor:pointer;text-align:center}.elementor-widget-video .elementor-custom-embed-image-overlay:hover .elementor-custom-embed-play i{opacity:1}.elementor-widget-video .elementor-custom-embed-image-overlay img{display:block;width:100%;aspect-ratio:var(--video-aspect-ratio);-o-object-fit:cover;object-fit:cover;-o-object-position:center center;object-position:center center}@supports not (aspect-ratio:1\/1){.elementor-widget-video .elementor-custom-embed-image-overlay{position:relative;overflow:hidden;height:0;padding-bottom:calc(100% \/ var(--video-aspect-ratio))}.elementor-widget-video .elementor-custom-embed-image-overlay img{position:absolute;top:0;right:0;bottom:0;left:0}}.elementor-widget-video .e-hosted-video .elementor-video{-o-object-fit:cover;object-fit:cover}.e-con-inner>.elementor-widget-video,.e-con>.elementor-widget-video{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<iframe class=\"elementor-video-iframe\" allowfullscreen allow=\"clipboard-write\" title=\"vimeo Video Player\" src=\"https:\/\/player.vimeo.com\/video\/816997804?color&amp;autopause=0&amp;loop=0&amp;muted=0&amp;title=0&amp;portrait=0&amp;byline=0#t=\"><\/iframe>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-49520b3\" data-id=\"49520b3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-486de4c elementor-widget elementor-widget-heading\" data-id=\"486de4c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Quick &amp; easy tissue preservation protocol<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-28fda20 elementor-widget elementor-widget-text-editor\" data-id=\"28fda20\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Our streamlined protocol takes just<b> 4-6 days<\/b>, without the variability of tissue embedding via hydrogel or paraffin. Reagents are <b>non-toxic<\/b> and can be easily disposed of after use.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-db414db elementor-widget elementor-widget-image\" data-id=\"db414db\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"237\" src=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/SHIELD-schematic-withtext-Med.png\" class=\"attachment-full size-full wp-image-1511\" alt=\"Figure showing SHIELD tissue preservation mechanism\" srcset=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/SHIELD-schematic-withtext-Med.png 1024w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/SHIELD-schematic-withtext-Med-300x69.png 300w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/SHIELD-schematic-withtext-Med-768x178.png 768w, https:\/\/lifecanvastech.com\/wp-content\/uploads\/2022\/07\/SHIELD-schematic-withtext-Med-600x139.png 600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0a5ec8a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0a5ec8a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-d4ab3a3\" data-id=\"d4ab3a3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1d340cd elementor-widget elementor-widget-heading\" data-id=\"1d340cd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Two SHIELD kit sizes<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6538362 elementor-widget elementor-widget-text-editor\" data-id=\"6538362\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>250 mL: <\/b>Preserves 25 whole mouse brains or comparably sized samples.<\/p><ul><li>250 mL SH-Epoxy<\/li><li>125 mL SH-Buffer<\/li><li>500 mL SH-ON<\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4390d42 elementor-widget elementor-widget-text-editor\" data-id=\"4390d42\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>500 mL:<\/b> Preserves 50 whole mouse brains or comparably sized samples.<\/p>\n<ul>\n<li>500 mL SH-Epoxy<\/li>\n<li>250 mL SH-Buffer<\/li>\n<li>1000 mL SH-ON<\/li>\n<\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-95b306d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"95b306d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-e99a1d7\" data-id=\"e99a1d7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e623e8c elementor-align-center elementor-widget elementor-widget-button\" data-id=\"e623e8c\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/lifecanvastech.com\/shop\/tissue-preservation-shield-solution\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-left\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-cart-plus\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Add to cart (U.S.)<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3dd66e9\" data-id=\"3dd66e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-77715d6 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"77715d6\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/lifecanvastech.com\/contact-us\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-left\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-envelope\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Request quote (International)<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e3a6f44\" data-id=\"e3a6f44\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-381f386 elementor-widget elementor-widget-image\" data-id=\"381f386\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/elementor\/thumbs\/SHIELD2-100dpi-psfovdqq7j9rdjh20cddl612ho3gvaum6hzeuivn5y.png\" title=\"SHIELD2-100dpi\" alt=\"SHIELD reagent bottles\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9a3134f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9a3134f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-bcb1f7f\" data-id=\"bcb1f7f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f2c5ae1 elementor-widget elementor-widget-heading\" data-id=\"f2c5ae1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Documentation<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9413cdd elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9413cdd\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/lifecanvastech.com\/wp-content\/plugins\/elementor\/assets\/css\/widget-icon-list.min.css\">\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2021\/11\/SHIELDEpoxy_MSDS.pdf\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-paperclip\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">MSDS: SHIELD Epoxy<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2021\/11\/SHIELDBuffer_MSDS.pdf\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-paperclip\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">MSDS: SHIELD Buffer<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2021\/11\/SHIELDONBuffer_MSDS.pdf\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-paperclip\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">MSDS: SHIELD ON<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/04\/Reagents-Brochure-041823.pdf\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-paperclip\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Reagents Datasheet<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-348a863\" data-id=\"348a863\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1105c66 elementor-widget elementor-widget-heading\" data-id=\"1105c66\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Protocols<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95517fd elementor-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"95517fd\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/sites.google.com\/lifecanvastech.com\/protocol\/outline\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-star\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Visit Our Protocol Wiki Here!<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-de8c099 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"de8c099\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-819df46\" data-id=\"819df46\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d404c90 elementor-widget elementor-widget-heading\" data-id=\"d404c90\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Recent publications citing SHIELD<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-839d5d6 elementor-widget elementor-widget-shortcode\" data-id=\"839d5d6\" data-element_type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-shortcode\"><div id=\"drts-platform-render-662fe67451a45-1\" class=\"drts drts-main drts-view-shortcode\"><div class=\"drts-view-entities-container drts-view-entities-container-list\" data-view-bundle-name=\"publications_dir_ltg\" data-view-name=\"shield\" data-view-url=\"https:\/\/lifecanvastech.com\/directory-publications\/?settings_cache_id=d591e1d9b515cad585922bd0dadea858&amp;sort=field_date_established%2Cdesc\">\n    <div class=\"drts-view-entities-header drts-bs-mb-4\"><\/div>\n\n\n<div class=\"drts-view-entities drts-view-post-entities drts-view-entities-list\">\n    <div class=\"drts-view-entities-list-row\">\n    <div class=\"drts-row drts-gutter-sm\">\n        <div class=\"drts-col-12 drts-view-entity-container\">\n            <div id=\"drts-platform-render-662fe67451a45-1-post-3150\" data-entity-id=\"3150\" class=\"drts-entity drts-entity-post drts-display drts-display--summary-recent-publications drts-display-default-summary\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\" data-display-type=\"entity\" data-display-name=\"summary-recent_publications\"><div data-name=\"entity_field_post_title\" class=\"drts-display-element drts-display-element-entity_field_post_title-1 drts-display-element-inlineable  drts-bs-mt-3 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><a href=\"https:\/\/www.cell.com\/neuron\/pdf\/S0896-6273(23)00974-1.pdf\" target=\"_blank\" title=\"Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity.\" class=\" drts-entity-permalink drts-entity-3150\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\">Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity.<\/a><\/div>\n<div data-name=\"entity_field_field_authors\" class=\"drts-display-element drts-display-element-entity_field_field_authors-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><p>Dong Yang, Yu Wang, Tianbo Qi, Xi Zhang, Leyao Shen, Jingrui Ma, Zhengyuan Pang, Neeraj K. Lal, Daniel B. McClatchy, Saba Heydari Seradj, Verina H. Leung, Kristina Wang, Yi Xie, Filip S. Polli, Anton Maximov, Oscar Christian Gonzalez, Luis de Lecea, Hollis T. Cline, Vineet Augustine, John R. Yates III, and Li Ye.<\/p>\n<\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_journal\" class=\"drts-display-element drts-display-element-entity_field_field_journal-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Journal:<\/div><div class=\"drts-entity-field-value\">Neuron<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_date_established\" class=\"drts-display-element drts-display-element-entity_field_field_date_established-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Publication Date:<\/div><div class=\"drts-entity-field-value\"><time class=\"drts-datetime\" datetime=\"2024-03-20T00:00:00+00:00\">March 20, 2024<\/time><\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tag\" class=\"drts-display-element drts-display-element-entity_field_field_tag-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Research Area:<\/div><div class=\"drts-entity-field-value\">Neural Circuits, Neural Interfaces<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-2 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_tissue_species\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_species-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Species:<\/div><div class=\"drts-entity-field-value\">Mouse<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tissue_type\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_type-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Type:<\/div><div class=\"drts-entity-field-value\">Brain<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-3 drts-bs-mr-3 drts-bs-mb-3 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_products_cited\" class=\"drts-display-element drts-display-element-entity_field_field_products_cited-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Products Cited:<\/div><div class=\"drts-entity-field-value\">SHIELD, EasyIndex, SmartBatch+, SmartSPIM, SmartAnalytics, CRO Services<\/div><\/div><\/div><\/div>        <\/div>\n                <div class=\"drts-col-12 drts-view-entity-container\">\n            <div id=\"drts-platform-render-662fe67451a45-1-post-3151\" data-entity-id=\"3151\" class=\"drts-entity drts-entity-post drts-display drts-display--summary-recent-publications drts-display-default-summary\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\" data-display-type=\"entity\" data-display-name=\"summary-recent_publications\"><div data-name=\"entity_field_post_title\" class=\"drts-display-element drts-display-element-entity_field_post_title-1 drts-display-element-inlineable  drts-bs-mt-3 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.01.15.575766v1\" target=\"_blank\" title=\"Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawal\" class=\" drts-entity-permalink drts-entity-3151\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\">Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawal<\/a><\/div>\n<div data-name=\"entity_field_field_authors\" class=\"drts-display-element drts-display-element-entity_field_field_authors-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><p>Rhiana C. Simon, Weston T. Fleming, Pranav Senthilkumar, Brandy A. Briones1,2, Kentaro K. Ishii, Madelyn M. Hjort, Madison M. Martin, Koichi Hashikawa, Andrea D. Sanders, Sam A. Golden, Garret D. Stuber.<\/p>\n<\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_journal\" class=\"drts-display-element drts-display-element-entity_field_field_journal-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Journal:<\/div><div class=\"drts-entity-field-value\">bioRxiv<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_date_established\" class=\"drts-display-element drts-display-element-entity_field_field_date_established-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Publication Date:<\/div><div class=\"drts-entity-field-value\"><time class=\"drts-datetime\" datetime=\"2024-01-16T00:00:00+00:00\">January 16, 2024<\/time><\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tag\" class=\"drts-display-element drts-display-element-entity_field_field_tag-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Research Area:<\/div><div class=\"drts-entity-field-value\">Neural Circuits, Other<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-2 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_tissue_species\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_species-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Species:<\/div><div class=\"drts-entity-field-value\">Mouse<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tissue_type\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_type-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Type:<\/div><div class=\"drts-entity-field-value\">Brain, Heart<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-3 drts-bs-mr-3 drts-bs-mb-3 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_products_cited\" class=\"drts-display-element drts-display-element-entity_field_field_products_cited-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Products Cited:<\/div><div class=\"drts-entity-field-value\">SHIELD, EasyIndex, SmartClear, SmartSPIM<\/div><\/div><\/div><\/div>        <\/div>\n                <div class=\"drts-col-12 drts-view-entity-container\">\n            <div id=\"drts-platform-render-662fe67451a45-1-post-3111\" data-entity-id=\"3111\" class=\"drts-entity drts-entity-post drts-display drts-display--summary-recent-publications drts-display-default-summary\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\" data-display-type=\"entity\" data-display-name=\"summary-recent_publications\"><div data-name=\"entity_field_post_title\" class=\"drts-display-element drts-display-element-entity_field_post_title-1 drts-display-element-inlineable  drts-bs-mt-3 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><a href=\"https:\/\/assets.researchsquare.com\/files\/rs-3470830\/v1_covered_1a182993-7e1c-4d9f-bf5f-7b5bd111861c.pdf?c=1698954475\" target=\"_blank\" title=\"A topographical atlas of \u03b1-synuclein cell type-specfic expression in adult mouse brain and peripheral organs\" class=\" drts-entity-permalink drts-entity-3111\" data-type=\"post\" data-content-type=\"directory__listing\" data-content-name=\"publications_dir_ltg\">A topographical atlas of \u03b1-synuclein cell type-specfic expression in adult mouse brain and peripheral organs<\/a><\/div>\n<div data-name=\"entity_field_field_authors\" class=\"drts-display-element drts-display-element-entity_field_field_authors-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 \" style=\"\"><p>Maxime W C Rousseaux, Haley Geertsma, Zoe Fisk, Lillian Sauline, Alice Prigent, Kevin Kurgat, Steve Callaghan, Julianna Tomlinson, Michael Henderson<\/p>\n<\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-1 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_journal\" class=\"drts-display-element drts-display-element-entity_field_field_journal-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Journal:<\/div><div class=\"drts-entity-field-value\">Research Square<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_date_established\" class=\"drts-display-element drts-display-element-entity_field_field_date_established-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Publication Date:<\/div><div class=\"drts-entity-field-value\"><time class=\"drts-datetime\" datetime=\"2023-11-02T00:00:00+00:00\">November 2, 2023<\/time><\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tag\" class=\"drts-display-element drts-display-element-entity_field_field_tag-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Research Area:<\/div><div class=\"drts-entity-field-value\">Neurodegeneration<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-2 drts-bs-mr-3 drts-bs-mb-2 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_tissue_species\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_species-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Species:<\/div><div class=\"drts-entity-field-value\">Mouse<\/div><\/div><div class=\"drts-display-group-element-separator\"><\/div><div data-name=\"entity_field_field_tissue_type\" class=\"drts-display-element drts-display-element-entity_field_field_tissue_type-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Tissue Type:<\/div><div class=\"drts-entity-field-value\">Brain, Spinal Cord, GI Tract<\/div><\/div><\/div>\n<div data-name=\"group\" class=\"drts-display-element drts-display-element-group-3 drts-bs-mr-3 drts-bs-mb-3 drts-bs-ml-3 drts-display-group-inline drts-display-element-no-header\" style=\"\"><div data-name=\"entity_field_field_products_cited\" class=\"drts-display-element drts-display-element-entity_field_field_products_cited-1 drts-display-element-inlineable \" style=\"\"><div class=\"drts-entity-field-label drts-entity-field-label-type-custom\">Products Cited:<\/div><div class=\"drts-entity-field-value\">SHIELD, CRO Services<\/div><\/div><\/div><\/div>        <\/div>\n            <\/div>\n<\/div><\/div>\n\n<div class=\"drts-view-entities-footer drts-bs-mt-4\"><\/div><\/div>\n\n<script type=\"text\/javascript\">document.addEventListener(\"DOMContentLoaded\", function(event) { var $ = jQuery;\nDRTS.init($(\"#drts-platform-render-662fe67451a45-1\"));\n});<\/script><\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f817172 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f817172\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/lifecanvastech.com\/publications\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-left\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-book\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Search more publications<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3075daa elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3075daa\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34eae50\" data-id=\"34eae50\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-df5eba3 elementor-widget elementor-widget-heading\" data-id=\"df5eba3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Further reading<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a10a7fd elementor-grid-eael-col-2 elementor-grid-tablet-eael-col-2 elementor-grid-mobile-eael-col-1 elementor-widget elementor-widget-eael-post-grid\" data-id=\"a10a7fd\" data-element_type=\"widget\" data-settings=\"{&quot;eael_post_grid_columns&quot;:&quot;eael-col-2&quot;,&quot;eael_post_grid_columns_tablet&quot;:&quot;eael-col-2&quot;,&quot;eael_post_grid_columns_mobile&quot;:&quot;eael-col-1&quot;}\" data-widget_type=\"eael-post-grid.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div id=\"eael-post-grid-a10a7fd\" class=\"eael-post-grid-container\">\n            <div class=\"eael-post-grid eael-post-appender eael-post-appender-a10a7fd eael-post-grid-style-two\" data-layout-mode=\"grid\"><article class=\"eael-grid-post eael-post-grid-column\" data-id=\"2926\">\n        <div class=\"eael-grid-post-holder\">\n            <div class=\"eael-grid-post-holder-inner\"><div class=\"eael-entry-wrapper\"><header class=\"eael-entry-header\"><h3 class=\"eael-entry-title\"><a\n                                    class=\"eael-grid-post-link\"\n                                    href=\"https:\/\/lifecanvastech.com\/ihc-vs-3d-histology\/\"\n                                    title=\"Immunohistochemistry (IHC) vs. 3D Histology\">Immunohistochemistry (IHC) vs. 3D Histology<\/a><\/h3><\/header><div class=\"eael-entry-content\">\n                                    <div class=\"eael-grid-post-excerpt\"><p>Immunohistochemistry (IHC) and 3D histology are different approaches to detecting specific proteins in biological tissue.<\/p><\/div>\n                                <\/div><div class=\"eael-entry-header-after style-two\"><div class=\"eael-entry-meta\"><span class=\"eael-meta-posted-on\"><i class=\"far fa-clock\"><\/i><time datetime=\"August 9, 2023\">August 9, 2023<\/time><\/span><\/div><\/div><\/div><\/div>\n        <\/div>\n    <\/article><article class=\"eael-grid-post eael-post-grid-column\" data-id=\"200\">\n        <div class=\"eael-grid-post-holder\">\n            <div class=\"eael-grid-post-holder-inner\"><div class=\"eael-entry-wrapper\"><header class=\"eael-entry-header\"><h3 class=\"eael-entry-title\"><a\n                                    class=\"eael-grid-post-link\"\n                                    href=\"https:\/\/lifecanvastech.com\/three-easy-steps-to-superior-tissue-preservation-with-shield\/\"\n                                    title=\"Superior tissue preservation with SHIELD\">Superior tissue preservation with SHIELD<\/a><\/h3><\/header><div class=\"eael-entry-content\">\n                                    <div class=\"eael-grid-post-excerpt\"><p>The SHIELD kit provides optimal tissue preservation by stabilizing molecular features & tissue architecture with flexible epoxide bonds.<\/p><\/div>\n                                <\/div><div class=\"eael-entry-header-after style-two\"><div class=\"eael-entry-meta\"><span class=\"eael-meta-posted-on\"><i class=\"far fa-clock\"><\/i><time datetime=\"September 17, 2021\">September 17, 2021<\/time><\/span><\/div><\/div><\/div><\/div>\n        <\/div>\n    <\/article><article class=\"eael-grid-post eael-post-grid-column\" data-id=\"394\">\n        <div class=\"eael-grid-post-holder\">\n            <div class=\"eael-grid-post-holder-inner\"><div class=\"eael-entry-wrapper\"><header class=\"eael-entry-header\"><h3 class=\"eael-entry-title\"><a\n                                    class=\"eael-grid-post-link\"\n                                    href=\"https:\/\/lifecanvastech.com\/sample-preservation-with-shield-for-tissue-clearing-and-3d-histology\/\"\n                                    title=\"SHIELD for tissue clearing and 3D histology\">SHIELD for tissue clearing and 3D histology<\/a><\/h3><\/header><div class=\"eael-entry-content\">\n                                    <div class=\"eael-grid-post-excerpt\"><p>Without SHIELD preservation, many tissue clearing techniques can lead to significant sample degradation and loss of biomolecular information.<\/p><\/div>\n                                <\/div><div class=\"eael-entry-header-after style-two\"><div class=\"eael-entry-meta\"><span class=\"eael-meta-posted-on\"><i class=\"far fa-clock\"><\/i><time datetime=\"May 15, 2020\">May 15, 2020<\/time><\/span><\/div><\/div><\/div><\/div>\n        <\/div>\n    <\/article><article class=\"eael-grid-post eael-post-grid-column\" data-id=\"429\">\n        <div class=\"eael-grid-post-holder\">\n            <div class=\"eael-grid-post-holder-inner\"><div class=\"eael-entry-wrapper\"><header class=\"eael-entry-header\"><h3 class=\"eael-entry-title\"><a\n                                    class=\"eael-grid-post-link\"\n                                    href=\"https:\/\/lifecanvastech.com\/tissue-processing-in-the-21st-century\/\"\n                                    title=\"Tissue processing in the 21st century\">Tissue processing in the 21st century<\/a><\/h3><\/header><div class=\"eael-entry-content\">\n                                    <div class=\"eael-grid-post-excerpt\"><p>Immunohistochemistry methods are laborious, error-prone, and expensive \u2013 intact tissue processing technologies resolve many of these issues.<\/p><\/div>\n                                <\/div><div class=\"eael-entry-header-after style-two\"><div class=\"eael-entry-meta\"><span class=\"eael-meta-posted-on\"><i class=\"far fa-clock\"><\/i><time datetime=\"March 18, 2019\">March 18, 2019<\/time><\/span><\/div><\/div><\/div><\/div>\n        <\/div>\n    <\/article><\/div>\n            <div class=\"clearfix\"><\/div>\n        <\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Exceptional tissue preservation Published by Park et al. in Nature Biotechnology 2018, our SHIELD reagent (AKA GE38) safeguards endogenous fluorescence, protein antigenicity, nucleic acids, and overall tissue architecture against physical and chemical stressors. The SHIELD tissue preservation method also protects tissue during fluorescent protein imaging and antibody labeling across multiple rounds. Compatible with: All PFA-fixed [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":783,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"content-type":"","footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Tissue Preservation with SHIELD<\/title>\n<meta name=\"description\" content=\"Our SHIELD tissue preservation method protects important molecular information, fluorescence, &amp; tissue architecture in PFA-fixed tissues.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lifecanvastech.com\/products\/shield\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tissue Preservation with SHIELD\" \/>\n<meta property=\"og:description\" content=\"Our SHIELD tissue preservation method protects important molecular information, fluorescence, &amp; tissue architecture in PFA-fixed tissues.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lifecanvastech.com\/products\/shield\/\" \/>\n<meta property=\"og:site_name\" content=\"LifeCanvas Technologies\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/lifecanvas\/\" \/>\n<meta property=\"article:modified_time\" content=\"2024-02-28T15:28:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@LifeCanvasTech\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lifecanvastech.com\/products\/shield\/\",\"url\":\"https:\/\/lifecanvastech.com\/products\/shield\/\",\"name\":\"Tissue Preservation with SHIELD\",\"isPartOf\":{\"@id\":\"https:\/\/lifecanvastech.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/lifecanvastech.com\/products\/shield\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/lifecanvastech.com\/products\/shield\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png\",\"datePublished\":\"2021-11-15T14:37:37+00:00\",\"dateModified\":\"2024-02-28T15:28:09+00:00\",\"description\":\"Our SHIELD tissue preservation method protects important molecular information, fluorescence, & tissue architecture in PFA-fixed tissues.\",\"breadcrumb\":{\"@id\":\"https:\/\/lifecanvastech.com\/products\/shield\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lifecanvastech.com\/products\/shield\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lifecanvastech.com\/products\/shield\/#primaryimage\",\"url\":\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png\",\"contentUrl\":\"https:\/\/lifecanvastech.com\/wp-content\/uploads\/2023\/02\/Tissue-Pres-Pipeline-Icons.png\",\"width\":1255,\"height\":215,\"caption\":\"Tissue Preservation - 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