Image Gallery

Mouse brain hemisphere labeled with 5 µg of goat anti-GFP (Encor Biotechnology, CAT# GPCA-GFP). Imaged at 1.8 µm lateral pixel size and 4 µm z-step.

 

a) eGFP acquired at 488-nm, 400-µm maximum intensity projection. Scale bar 250 µm.

b) anti-GFP acquired at 561-nm, 400-µm maximum intensity projection. Scale bar 250 µm.

c) Merged image of two MIPs, showing colocalization of endogenous GFP and anti-GFP labeling.

Mouse brain hemisphere with ChAT+ neurons in both the brainstem and basal forebrain with dense labeling of Neuropeptide Y throughout the hypothalamus.

 

Tissue immunolabeled anti-NPY (cyan) and anti-ChAT (magenta). Imaged at 4 µm Z-step and 1.8 µm XY pixel size.

 

Tissue courtesy of Hongwei Dong, Center for Integrative Connectomics (CIC) lab, USC.

Retrogradely labeled motor cortical neurons projecting to striatum via rabies virus expressing eGFP.

 

Sample courtesy of Byungkook Lim, UCSD.

Nuclear stain (SYTO16, in cyan) and vasculature stain (DyLight 649-conjugated tomato lectin,  pink).

 

Tissue courtesy of Translational Bioimaging Group, Barrow Neurological Institute.

Mouse duodenum segment, perfused with lectin (red) to label vasculature and immunolabeled with anti-Olfm4 stem cell marker (cyan). Imaged at 2 µm Z-step and 1.8 µm XY pixel size.

 

Sample courtesy of Suhail Chaudhry, Ferrara Bone Marrow Transplantation Lab, Icahn School of Medicine.

MIP (200µm) image showing TH labeling of Ventral Tegmental Area (VTA), Substantia Nigra (SN), Retrorubral Field (RF), and Locus Coeruleus (LC), highly populated with dopaminergic and noradrenergic neurons.

 

Imaged at 1.8 x 1.8 x 4 µm voxel size.

Imaged at 1.8 x 1.8 x 4 µm voxel size.

 

Sample courtesy of Helen Lai, UT Southwestern.

Tissue treated with lectin dye, labeling blood vessels with high specificity and signal-noise ratio.

 

15X objective, 1.5 x 1.5 x 1.8 mm region acquired at 1 µm Z-step.

Immunolabeled GFAP (cyan) and Beta-amyloid plaques (magenta) from the brain of a 5xFAD Alzheimer’s disease model mouse.

 

Imaged at 1.8 x 1.8 x 4 µm voxel size. Sample courtesy of Jonathan Epp, University of Calgary.

a) Radially-positioned hair cells within the spiral cavity of the cochlea surrounded by bone and nerve tissue.

b) Cut end of a nerve bundle.

 

MIP (200 µm) imaged at 4 µm z-step and 1.8 µm XY pixel size. Tissue courtesy of Rick A. Rogers, Harvard School of Public Health.