c-FOS+ cells in intact mouse brain hemisphere

Benefits of 3D tissue processing over traditional histology

c-FOS expression is an indicator of recent neural cell activity, making the detection of c-FOS+ cells a high priority for many neuroscientists. This image stack captures the hippocampus and dorsal cortex in the sagittal plane of a mouse brain left hemisphere stained with anti-c-FOS. These images were acquired with SmartSPIM at 3.6X magnification and 4 µm z-step.

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