LifeCanvas Technologies

SDS monomers rupture cell membrane and form micelles to facilitate tissue clearing

20 Oct How do detergents dissolve lipid membranes?

Posted at 14:42h in Science

As explained in several of our blogs, delipidation is a critical step in the tissue clearing process. Some form of lipid removal is present in almost all of the most popular clearing techniques, including CLARITY, iDISCO, SHIELD, and CUBIC. In the case of SHIELD and...

09 Apr Beginner’s guide to tissue clearing with LifeCanvas products

Posted at 06:00h in Science

New to tissue clearing? If so, you are in the right place! This guide will walk you through the tissue processing journey step by step. First, to ensure the sample retains endogenous fluorescence, protein antigenicity, and structural integrity throughout the clearing process, the tissue ...