SmartClear II Pro

The Multi-Purpose Tissue Clearing System You've Been Waiting For

SmartClear II Pro is compatible with many clearing techniques including:
 
  • CLARITY (Chung, Nature, 2013)
  • SWITCH (Murray, Cell, 2015)
  • MAP (Ku, Nature Biotechnology, 2016)
 

Rapid Immunostaining
with Unparalleled Uniformity

Multi-Purpose Function

Batch processing and customization: 5 whole mouse brains or 2 rat brains can be cleared simultaneously. Larger clearing chamber enables clearing of various sample types and sizes that can be customized according to your needs.

Cost-Effective Clearing of Bulk Quantity

Cost-effective and Eco-friendly: New-generation buffer set lasts around 10 days without loss of its clearing ability. Lower running costs for samples as the same volume of buffer is used regardless of size and number of samples.

Fast, Easy, and Reliable

Fast & Easy: Order of magnitude faster than passive clearing. Our ready-to-use technologies bring plug-and-play options to clearing.

 

Reliable: Prevents tissue damage with Stochastic Electrotransport technology (Kim, PNAS, 2015). Our nanoporous membranes (patent-pending) eliminate tissue contamination, tissue browning, black precipitates and tissue deformation while providing uniform clearing.

Perfect Clearing with Maximal FP Signal Preservation

FP Signals: Maximum preservation of Fluorescent Protein (FP) signals with optimized buffers that maintain pH.

 

Optical Clarity: Minimum light scatter. Removes lipid best for best antibody diffusion. Optimal imaging and staining quality that is compatible with SmartLabel, our rapid staining system for intact samples.

Various Sample Holders

L2P10_v1_EDIT

SC-L2P10

11mm (W) x 18mm (D) x 40mm (H) x 5
Clears 5 whole mouse brains

L2P11_v1_EDIT

SC-L2P11

3mm apart
Clears up to 10 1~2mm thick slices

L2P12_v1_EDIT

SC-L2P12

19mm (W) x 28mm (D) x 40mm (H) x 2
Clears 2 whole rat brains

L2P13_v1_EDIT

SC-L2P13

4mm (D) x 18 holes
Clears up to 18 circular disk-shape tissues

L2P14_v1_EDIT

SC-L2P14

15mm (bottom diameter) x 19mm (top diameter) x 40mm (H) x 2
Clears 2 whole rat brains

Reagents

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Clearing Buffer

Optimized for tissue clearing
Long life time (up to 10 days)
Eco-Friendly

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Optical Clearing Solution (RI=1.46)

Formulated for best performance
with CLARITY, SWITCH, and MAP
Cost-effective and convenient